The Symptom Experience and Management in People with HIV Who Underwent Antiretroviral Therapy During the Covid-19 Pandemic in Bali, Indonesia

Nyoman Agus Jagat Raya; Ni Kadek Ayu Suarningsih

doi:10.21776/ub.jik.2022.010.02.2

Authors

Nyoman Agus Jagat Raya Medical Surgical Nursing Division, Nursing Department, Faculty of Medicine, Udayana University
Ni Kadek Ayu Suarningsih Medical Surgical Nursing Division, Nursing Department, Faculty of Medicine, Udayana University

DOI:

https://doi.org/10.21776/ub.jik.2022.010.02.2

Keywords:

Antiretroviral, COVID-19, HIV / AIDS, Symptom experience, Symptom management

Abstract

Antiretroviral (ARV) therapy does not only provide some benefits but also has side effects that cause symptoms experienced by people with HIV (PWH). Strategies for effective symptom management were needed, especially during the COVID-19 pandemic. The purpose of this study was to explore the symptom experience and management strategies in PWH during the COVID-19 pandemic. A qualitative phenomenology design was used. A cross-sectional with purposive and snowball sampling techniques was used from July to October 2021. Eight participants joined an in-depth interview based on the criteria of the participants, such as people who were infected with HIV, 18 years or older, on ARV therapy, and willing to sign the informed consent. Thematic analysis was used after data saturation was reached. Three themes were found in this study; 1) The symptoms of ARV side effects, which included physical and psychological symptoms that appeared in PWH; 2) The symptom management of ARV side effects, which described the history of hospitalization, pharmacological and non-pharmacological management; 3) The symptom condition during the COVID-19 pandemic. The symptom experience of ARV side effects required strategies to manage the appearance of the symptoms, especially those amid the COVID-19 pandemic. This study could become fundamental evidence to consider in providing nursing care to PWH and supporting the symptom management model among PWH further.

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References

Callis, A. (2020). Application of the Roy Adaptation Theory to a care program for nurses. Applied Nursing Research, 56, 1-6. https://doi.org/10.1016/j.apnr.2020.151340.
Chen, W.-T., Shiu, C.-S., Yang, J. P., Simoni, J. M., Goldsen, K. I., Lee, S.-H., & Zhao, H. (2013). Antiretroviral therapy (ART) side effect impacted on quality of life, and depressive symptomatology: A mixed-method study. Journal AIDS and Clinical Research, 4, 218. https://doi.org/10.4172/2155-6113.1000218.
Davies, M.-A. (2020). HIV and risk of COVID-19 death: A population cohort study from the Western Cape Province, South Africa. medRvix: the preprint server for health sciences.
Edelman, E. J., Gordon, K., Barradas, M. C., & Justice, A. C. (2012). Patient-reported symptoms on the antiretroviral regimen efavirenz/emtricitabine/tenofovir. AIDS Patient Care and STDs, 26(6), 312-319. https://doi.org/10.1089/apc.2012.0044.
Eller, L. S., Kirksey, K. M., Nicholas, P. K., Corless, I. B., Holzemer, W. L., Wantland, D. J., et al. (2013). A randomized controlled trial of an HIV/AIDS symptom management manual for depressive symptoms. AIDS Care, 25(4), 391-399. https://doi.org/10.1080/09540121.2012.712662.
Fonsah, J. Y., Njamnshi, A. K., Kouanfack, C., Qiu, F., Njamnshi, D. M., Tagny, C., Nchindap, E., Kenmogne, L., Mbanya, D., Heaton, R, & Kanmogne, G.D. (2017). Adherence to antiretroviral therapy (ART) in YaoundeÂ-Cameroon: Association with opportunistic infections, depression, ART regimen and side effects. PLoS ONE, 12(1), https://doi.org/10.1371/journal.pone.0170893.
Humphreys, J., Donesky, D., Dracup, K., Lee, K. A., Puntillo, K., Faucett, J., Aouzerat, B., Miaskowski, C., Baggott, C., Carrieri-Kohlman, V., Barger, M., Franck, L., Kennedy, C., & UCSF School of Nursing Symptom Management Faculty Group. (2014). A middle range theory of symptom management. In M.J. Smith & P.R. Liehr (Eds.), Middle range theory for nursing (3rd ed.) (pp.141-164). New York: Springer Publishing Company.
Karjadi, T., Maria, S., Yunihastuti, E., Widhani, A., Kurniati, N., & Imran, D. (2021). Knowledge, attitude, behavior, and socioeconomic conditions of people living with HIV in Indonesia during the COVID-19 pandemic: A cross-sectional study. HIV/AIDS - Research and Palliative Care, 13, 1045–1054. https://doi.org/10.2147/HIV.S333469.
Klatt, E. C. (2017). Pathology of HIV/AIDS. Retrieved 2017, from Retrieved from https://library.med.utah.edu/WebPath/AIDS2017.PDF
Meintjes, G., Moorhouse, M. A., Carmona, S., Davies, N., Dlamini, S., van Vuuren, C., Manzini, T., Mathe, M., Moosa, Y., Nash, J., Nel, J., Pakade, Y., Woods, J., Zyl, G.V., Conradie, F., & Venter, F. (2017). Adult antiretroviral therapy guidelines 2017. Southern African Journal of HIV Medicine, 18(1), a776. https://doi.org/10.4102/ sajhivmed.v18i1.776.
Menezes de Padua, C., Braga, L., & Mendicino, C. (2017). Adverse reactions to antiretroviral therapy: A prevalent concern. The Revista Panamericana de Salud Pública, 41(e84). https://doi.org/10.26633/RPSP.2017.84.
Mirzaei, H., McFarland, W., Karamouzian, M., & Sharifi, H. (2020). COVID-19 among people living with HIV: A systematic review. AIDS and Behavior, 1-8. https://doi.org/10.1007/s10461-020-02983-2.
Modeste, R. R., & Majeke, S. J. (2014). Sources and types of information on self-care symptom management strategies for HIV and AIDS. Curationis, 37(1), http://dx.doi.org/10.4102/curationis.v37i1.127.
Panel on Antiretroviral Guidelines for Adults and Adolescents. (2018). Guidelines for the use of antiretroviral agents in adults and adolescents living with HIV. Department of Health and Human Service. Retrieved 2020, from AIDS Info: http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf
Pantelic, M., Martin, K., Fitzpatrick, C., Nixon, E., Tweed, M., Spice, W., Jones, M., Darking, M., Whetham, J., & Vera, J.H. (2021). “I have the strength to get through this using my past experiences with HIV”: findings from a mixed-method survey of health outcomes, service accessibility, and psychosocial wellbeing among people living with HIV during the Covid-19 pandemic. AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV, 1-7. https://doi.org/10.1080/09540121.2021.1975628.
Pusat Data dan Informasi Kesehatan Kemenkes RI. (2020). HIV AIDS. Retrieved 2021, from Kementerian Kesehatan Republik Indonesia: https://www.kemkes.go.id/download.php?file=download/pusdatin/infodatin/infodatin%202020%20HIV.pdf
Quatremère, G., Guiguet, M., Girardi, P., Liaud, M.-N., Mey, C., Benkhoucha, C., Barbier, F., Cattaneo, G., Simon, A., & Castro, D.R. (2017). How are women living with HIV in France coping with their perceived side effects of antiretroviral therapy? Results from the EVE study. PLoS ONE, 12(3), e0173338. https://doi.org/10.1371/journal.pone.0173338.
Raya, N., & Nilmanat, K. (2021). Experience and management of stigma among persons living with HIV in Bali, Indonesia: A descriptive study. Japan Journal of Nursing Science, 18(e12391), 1-11. https://doi.org/10.1111/jjns.12391.
Siagian, T. H. (2020). Mencari kelompok berisiko tinggi terinfeksi virus corona dengan discourse network analysis. Jurnal Kebijakan Kesehatan Indonesia, 9(2), 98-106. Retrieved from https://journal.ugm.ac.id/jkki/article/view/55475/27989.
Siewe Fodjo, J., Villela, E., Hees, S., dos Santos, T.T., Vanholder, P., Reyntiens, P., den Bergh, R.V., & Colebunders, R.. (2020). Impact of the COVID-19 pandemic on the medical follow-up and psychosocial well-being of people living with HIV: A cross-sectional survey. Journal of Acquired Immune Deficiency Syndromes, 85(3), 257–262. https://doi.org/10.1097/QAI.0000000000002468.
UNAIDS. (2020). Global HIV Statistic. Retrieved 2021, from The Joint United Nations Programme on HIV and AIDS: https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf
Voss, J. G. (2013). Developing evidence-based symptom management guideline in HIV care: What have we learned? Journal of the Association of Nurses in AIDS Care, 24(1S), S1-S4. http://dx.doi.org/10.1016/j.jana.2012.10.001.
Wakeham, K., Harding, R., Levin, J., Ratanshi, R. P., Kamali, A., & Lallo, D. G. (2018). The impact of antiretroviral therapy on symptom burden among HIV outpatients with low CD4 count in rural Uganda: nested longitudinal cohort study. BMC Palliative Care, 17(8), https://doi.org/10.1186/s12904-017-0215-y.
Zhu, Z., Hu, Y., Li, H.-w., Bao, M.-j., Zhang, L., Zha, L-j., Hou, X-h., & Lu, H-z. (2018). The implementation and evaluation of HIV symptom management guidelines: A preliminary study in China. International Journal of Nursing Sciences, 5(4), 315–321. https://doi.org/10.1016/j.ijnss.2018.08.005.