THE DIFFERENCES OF CORRELATION OF THE TIMI, GRACE, AND KILLIP RISK SCORES AS PREDICTOR PROGNOSIS PATIENTS WITH NON ST-ELEVATION MYOCARD INFARCTION ACUTE CORONARY SYNDROME IN ICCU RSUD DR.ISKAK TULUNGAGUNG

Authors

  • Rina Anggraini Jurusan Keperawatan Fakultas Kedokteran Universitas Brawijaya
  • Titin Andri Wihastuti Jurusan Keperawatan Fakultas Kedokteran Universitas Brawijaya
  • Dewi Kartikawatiningsih Jurusan Keperawatan Fakultas Kedokteran Universitas Brawijaya

DOI:

https://doi.org/10.21776/ub.jik.2018.006.01.8

Keywords:

ACS, NSTEMI, Skor Risiko (TIMI, GRACE, Killip), Length of Stay (LOS)

Abstract

Acute Coronary Syndromes is the leading cause of short-term and long –term mortality. An aggressive treatment approach has the potential to change the prognosis of patients with ACS, although its depends on risk factors. There are several risk scores  such as Thrombholysis in Myocardial Infarction (TIMI), Global Registry of Acute Coronary Events (GRACE), and Killip. The aim of this study is to analyse the differences of correlation of TIMI, GRACE, and Killip risk scores as predictor Length Of Stay patients with Non St-Elevation Myocard Infarction ACS. The method of this study utilized an analytic observational design with the cohort retrospective. The research was conducted at RSUD Dr.Iskak Tulungagung used 98 samples of medical records patient with NSTEMI ACS in the past 8 months (January-August 2017). The data collection techniques was completing risk score of TIMI, GRACE, and Killip and Length of Stay patient in ICCU ward. The results and analyse of Spearman Rank showed that TIMI has p = 0,000 r = 0.466,  GRACE p = 0,000 r = 0.598, and Killip p = 0,000 r = 0.441 (p < 0,05), so that it can be said that there was  significant differences between the risk score of TIMI, GRACE and Killip as predictor prognosis patient with NSTEMI ACS. It can be concluded that the TIMI, GRACE and Killip risk scores have correlation as predictor prognosis patient with NSTEMI ACS, which is GRACE risk score has superior to TIMI and Killip.

References

  • Antoni ML, Boden H, Delgado V, Boersma E, Fox K, Schalij MJ, Bax JJ. 2012. Relationship between discharge heart rate and mortality in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Eur Heart J 2012;33:96–102.doi:10.1093/euroheartj/ehr293.Epub 2011 Aug 22.
  • Backus, BE., Six, AJ., Kelder, JH., Gibler, WB., Moller,FL., Doevendans, PA. 2011. Risk Scores For Patient With Chest Pain: Evaluation In The Emergency Department. Current cardiology reviews, 2011, vol.7, No.1
  • Ben, S. H., Ouali, S., Hammas, S., Bougmiza, I., Gribaa, R., Ghannem, K., et al. 2011. Correlation of TIMI risk score with angiographic extent and severity of coronary artery disease in non ST-elevation acute coronary syndromes. Ann Cardiol Angeiol 2011; 60:87-91.
  • Bueno, H., Avilles, FF. 2012. Use Of Risk Scores In Acute Coronary Syndromes. Heart 2012 98: 162-168.doi:10.1136/heartjnl-2011-300129
  • El-Menyar A., Zubaid, M., AlMahmeed, W., Sulaiman, K., Alnabti, A., Singh, R., Al, SJ. 2012. Killip Classification in Patients With Acute Coronary Syndrome: Insight From a Multicenter Registry. Am J Emerg Med. 2012 Jan;30(1):97-103. doi: 10.1016/j.ajem.2010.10.011. Epub 2010 Dec 14
  • European Society of Cardiology Clinical Practice Guidelines. 2011. Acute Coronary Syndromes (ACS) in patients presenting without persistent ST-segment elevation (management of), Eur. Heart J. 32 (2011) 2999–3054.
  • Fillipiak KJ., Koltowski L, Grabowski M, Karpinski G, Glowzynska R, Huzcek Z, Kochman J, Majstrak F, et al. 2014. Comparison of the seven-year predictive value of sixrisk scores in acute coronary syndrome patients: GRACE, TIMI, SIMPLE, ZWOLLE, and BANACH. KardiolPol.2014;72(2):155-65,doi:10.5603/KP.a2013.0216. Epub 2013 Aug 30.
  • Garcia S, Canoniero M, Peter A, de Marchena E, Ferreira A. Correlation of TIMI risk score with angiographic severity and extent coronary artery disease in patient with non ST-elevation acute coronary syndromes. Am J Cardiol 2004;93:813-6
  • Jensen, MT., Kaiser, C., Sandsten, KE., Alber, H., Wanitshcek, M., Jensen, JS., Pedersen, S., Soerensen, R., et al. 2013. Heart rate at discharge and long-term prognosis following percutaneous coronary intervention in stable and acute coronary syndromes–results from the BASKET PROVE trial. Int J Cardiol 2013;168:3802–6.
  • Khalil, R.,Han, Lei., Quan, He. 2009. The use of risk scores for stratification of non-ST elevation acute coronary syndrome patients. exp Clin Cardiol 2009;14(2):e25-e30.
  • LaMorte, WW. 2016. Advantages and Disadvantages of Cohort Studies. Boston University School of Public Health
  • Lakhani, MS., Qadir, F., Hanif, B., Farooq, S., Khan, M. Correlation of Thrombolysis in Myocardial Infarction (TIMI) risk score with extent of coronary artery disease in patients with acute coronary syndrome. J Pak Med Assoc 2010;60:197-200
  • Lippi G, Sanchis-Gomar F, Cervellin G. 2016. Chest Pain, Dyspnea and Other Symptoms in Patients With Type 1 and 2 Myocardial Infarction. A literature review. Int J Cardiol 2016;215:20-2
  • Moghadam, MA., Safari, S., Moghadam, HA. 2016. Screening characteristics of TIMI score in predicting Acute Coronary Syndrome outcome; a diagnostic accuracy study. Emergency. 2017; 5 (1): e18
  • Nunez, G., Garcia-R., Luaces, M., Vivas,D., Agustin J., Ferrer G., Bordes, S., et al. 2010. Mild heart failure is a mortality marker after a non-ST-segment acute myocardial infarction. Elsevier. European Journal of Internal Medicine 21 (2010) 439–443
  • Nursalam. 2013. Konsep dan Penerapan Metodologi Penelitian Ilmu Keperawatan. Jakarta. Salemba Medika
  • PERKI. 2015. Pedoman Tatalaksana Sindrom Koroner Akut. Pehimpunan Dokter Spesialis Kardiovaskular Indonesia
  • Seronde MF, Geha R, Puymirat E, Chaib A, Simon T, Berard L, Drout E, et al. 2014. Discharge heart rate and mortality after acute myocardial infarction. Am J Med 2014;127: 954–62
  • World Health Organization (WHO). 2011. Global Atlas on Cardiovascular Disease Prevention and Control. Geneva: World Health Organization, 2011
  • Xu,t., Zhan, Y., Tan, X. 2016. The Relationship Between Heart Rate and Mortality of Patinets with Acute Coronary Syndromes in the Coronary Intervention Era. Medicine .2016Nov:95(46):e5371.doi:10.1097/MD.0000000005371
  • Zhu H, Xue H, Wang H, Chen Y, Zhou S, Tian F, Hu S, Wang J, Yang J, Zhang T. 2015. Risk Stratification and Prognostic Value of GRACE and TIMI risk scores for Female Patients with Non ST segment ElevationAcute Coronary Syndrome. Minerva Cardioangiol. 2015 Jun;63(3):171-8.Epub2014 Dec 11.



Published

2019-01-31

How to Cite

Anggraini, R., Wihastuti, T. A., & Kartikawatiningsih, D. (2019). THE DIFFERENCES OF CORRELATION OF THE TIMI, GRACE, AND KILLIP RISK SCORES AS PREDICTOR PROGNOSIS PATIENTS WITH NON ST-ELEVATION MYOCARD INFARCTION ACUTE CORONARY SYNDROME IN ICCU RSUD DR.ISKAK TULUNGAGUNG. Journal of Nursing Science Update (JNSU), 6(1), pp. 79–87. https://doi.org/10.21776/ub.jik.2018.006.01.8

Issue


Section

Articles


Most read articles by the same author(s)